热烈祝贺本刊主题编辑马光辉院士、青年编委魏炜研究员团队在纳微复合递送领域取得了重大突破，与军事医学研究院生物工程研究所王恒樑研究员及朱力研究员团队合作，开发出了一种具有“纳微复合”多级结构的单剂干粉吸入式疫苗研制平台技术，为呼吸道病毒的防治提供了新的解决方案。该成果于12月13日发表在《Nature》上（DOI：10.1038/s41586-023-06809-8）。
马光辉院士及魏炜研究员团队长期从事均一可控微球制备及生物剂型工程的研究，提出了纳微复合递送新理念，即将纳米级的药物或抗原颗粒与微米级的载体颗粒复合，形成具有多级结构的纳微复合颗粒，从而实现药物或疫苗的高效递送。该理念具有广泛的应用前景，尤其是在呼吸道疾病的防治方面，可以通过干粉吸入的方式，将疫苗直接送达肺部。特别是缓释微球抵达肺部后可以诱导快速、长期和高效的“黏膜-体液-细胞”三重免疫应答，有效阻断病毒的感染与传播，这是与传统注射式疫苗相比最显著的优势。
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