Synthesis and surface modification of magnetic particles for application in biotechnology and biomedicine--颗粒学报PARTICUOLOGY

Ma, Z., & Liu, H. (2007). Synthesis and surface modification of magnetic particles for application in biotechnology and biomedicine. China Particuology, 5(1), 1–10. https://doi.org/10.1016/j.cpart.2006.11.001

Synthesis and surface modification of magnetic particles for application in biotechnology and biomedicine

Zhiya Ma ^a, Huizhou Liu ^a *

a Laboratory of Separation Science and Engineering, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing 100080, China

10.1016/j.cpart.2006.11.001

Volume 5, Issues 1–2, February–April 2007, Pages 1-10

Received 23 March 2006, Accepted 28 November 2006, Available online 6 June 2007.

E-mail: hzliu@home.ipe.ac.cn

Highlights

Abstract

Magnetic particles have numerous applications in biotechnology and biomedicine. In this paper we reviewed the synthesis, surface modification and some applications of magnetic particles with focus on their synthesis and surface modification. Various methods have been developed for the production of magnetic particles (magnetic nanoparticles and magnetic composite particles). For future application magnetic particles must be modified to obtain stability and surface functional groups. Finally, the application of magnetic particles in magnetic separation, drug delivery, hyperthermia, and magnetic resonance imaging are discussed.

Graphical abstract

Keywords

Magnetic particles; Synthesis; Surface modification; Application

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