Photoelectrochemical glucose biosensor incorporating CdS nanoparticles--颗粒学报PARTICUOLOGY

Sun, J., Zhu, Y., Yang, X., & Li, C. (2009). Photoelectrochemical glucose biosensor incorporating CdS nanoparticles. Particuology, 7(5), 347–352. https://doi.org/10.1016/j.partic.2009.04.009

Photoelectrochemical glucose biosensor incorporating CdS nanoparticles

Jinjie Sun, Yihua Zhu^*, Xiaoling Yang, Chunzhong Li ^*

Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China

10.1016/j.partic.2009.04.009

Volume 7, Issue 5, October 2009, Pages 347-352

Received 31 December 2008, Revised 16 April 2009, Accepted 30 April 2009, Available online 2 September 2009.

E-mail: czli@ecust.edu.cn

Highlights

Abstract

A novel photoelectrochemical biosensor incorporating nanosized CdS semiconductor crystals with enzyme to enhance photochemical reaction has been investigated. CdS nanoparticles were synthesized by using dendrimer PAMAM as inner templates. The CdS nanoparticles and glucose oxidase (GOD) were immobilized on Pt electrode via layer-by-layer (LbL) technique to fabricate a biological–inorganic hybrid system. Under ultraviolet light, the photo-effect of the CdS nanoparticles showed enhancement of the biosensor to detect glucose. Pt nanoparticles were mixed into the Nafion film to immobilize the CdS/enzyme composites and to improve the charge transfer of the hybrid. Experimental results demonstrate the desirable characteristics of this biosensing system, e.g. a sensitivity of 1.83 μA/(mM cm²), lower detection limit (1 μM), and acceptable reproducibility and stability.

Graphical abstract

Keywords

CdS nanoparticles; PAMAM; Photoelectrochemical; Biosensor; Glucose oxidase; Layer-by-layer

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