Analysis and handling of bio-nanoparticles and environmental nanoparticles using electrostatic aerosol mobility--颗粒学报PARTICUOLOGY

Kallinger, P., Weiss, V. U., Lehner, A., Allmaier, G., & Szymanski, W. W. (2013). Analysis and handling of bio-nanoparticles and environmental nanoparticles using electrostatic aerosol mobility. Particuology, 11(1), 14–19. https://doi.org/10.1016/j.partic.2012.09.004

Analysis and handling of bio-nanoparticles and environmental nanoparticles using electrostatic aerosol mobility

Peter Kallinger ^a, Victor U. Weiss ^b, Angela Lehner ^b, Günter Allmaier ^b, Wladyslaw W. Szymanski ^a *

a University of Vienna, Faculty of Physics, Boltzmanngasse 5, A-1090 Vienna, Austria
b Vienna University of Technology, Institute of Chemical Technologies and Analytics, Getreidemarkt 9, A-1060 Vienna, Austria

10.1016/j.partic.2012.09.004

Volume 11, Issue 1, February 2013, Pages 14-19

Received 4 July 2012, Revised 28 August 2012, Accepted 12 September 2012, Available online 2 January 2013.

E-mail: w.szym@univie.ac.at

Highlights

► Parallel DMA provides simultaneous measurement and collection of nanoparticles with equivalent size.

► Non-destructive size determination of intact viruses can be done in airborne state.

► Size spectra of catalase indicate equilibrium between monomer and non-covalent biospecific complex.

Abstract

The successful application of differential mobility analysis for the characterization and manipulation of nanoparticles at atmospheric pressure has given rise to further development of this technique. The parallel differential mobility analyzer provides the possibility to simultaneously measure a size spectrum of nanoparticles and select a particular set of nanoparticles with a defined size for collection (as well as enrichment) and further orthogonal analysis (as for example electron microscopy, atomic force microscopy or mass spectrometry). Performing a high resolution measurement of electrical mobility diameters allows molecular weight determination of species with ultrahigh molecular masses in the mega Dalton range (e.g. protein complexes). The precise size measurement of the human rhinovirus has confirmed the potential of this technique to analyze even intact infectious human-pathogenic viruses. Moreover, the real-time measurement of nanoparticle occurrence in an urban environment confirms the versatility of the method presented here and its applicability also in other areas of importance.

Graphical abstract

Keywords

Nanoparticles; Environmental burden; Virus measurement; PDMA; GEMMA

文章导读