Green synthesis, characterization and physiological stability of gold nanoparticles from Stachys lavandulifolia Vahl extract--颗粒学报PARTICUOLOGY

Khademi-Azandehi, P., & Moghaddam, J. (2015). Green synthesis, characterization and physiological stability of gold nanoparticles from Stachys lavandulifolia Vahl extract. Particuology, 19, 22–26. https://doi.org/10.1016/j.partic.2014.04.00

Green synthesis, characterization and physiological stability of gold nanoparticles from Stachys lavandulifolia Vahl extract

Pooriya Khademi-Azandehi, Javad Moghaddam^*

Materials Engineering Department, Advanced Materials Research Center, Sahand University of Technology, P. O. Box 51335-1996, Tabriz, Iran

10.1016/j.partic.2014.04.007

Volume 19, April 2015, Pages 22-26

Received 13 January 2014, Revised 18 April 2014, Accepted 19 April 2014, Available online 18 July 2014.

E-mail: moghaddam@sut.ac.ir

Highlights

• Gold nanoparticles were synthesized using an aqueous extract derived from Stachys lavandulifolia Vahl.

• The method is biomedically nontoxic, economically affordable and practically simple.

• Gold nanoparticles are most probably capped with compounds, able to cross the blood–brain barrier.

• The synthesized gold nanoparticles are stable in physiological condition and over time.

Abstract

The synthesis of nontoxic stable gold nanoparticles is important for medical applications. An aqueous extract of the plant Stachys lavandulifolia Vahl was used to synthesize gold nanoparticles. This green method involved the S. lavandulifolia Vahl extract acting as a reducing and stabilizing agent. The nanoparticles were characterized by transmission electron microscopy, dynamic light scattering analysis and UV–vis absorption and Fourier transform-infrared spectroscopies. Stability under physiological conditions is important for medical applications. The stability of the nanoparticles was compared with that of conventional citrate-capped nanoparticles, under both synthetic and physiological conditions. The nanoparticles synthesized from the S. lavandulifolia Vahl extract were stable under physiological conditions, in contrast with conventional citrate-capped nanoparticles.

Graphical abstract

Keywords

Gold nanoparticle; Green synthesis; Stachys lavandulifolia Vahl; Physiological stability

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