Controllable microfluidic strategies for fabricating microparticles using emulsions as templates--颗粒学报PARTICUOLOGY

Zhang, M., Wang, W., Xie, R., Ju, X., Liu, Z., Jiang, L., . . . Chu, L. (2016). Controllable microfluidic strategies for fabricating microparticles using emulsions as templates. Particuology, 24, 18-31. https://doi.org/10.1016/j.partic.2015.08.001

Controllable microfluidic strategies for fabricating microparticles using emulsions as templates

Maojie Zhang ^a, Wei Wang ^a, Rui Xie ^a, Xiaojie Ju ^{a b}, Zhuang Liu ^a, Lu Jiang^c, Qianming Chen ^c, Liangyin Chu ^{a b *}

a School of Chemical Engineering, Sichuan University, Chengdu 610065, China
b State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China
c State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China

10.1016/j.partic.2015.08.001

Volume 24, February 2016, Pages 18-31

Received 29 April 2015, Revised 31 July 2015, Accepted 4 August 2015, Available online 26 September 2015, Version of Record 21 January 2016.

E-mail: chuly@scu.edu.cn

Highlights

• Microfluidic techniques for controllable generation of emulsions were reviewed.

• Microfluidic strategies for fabricating particles from diverse emulsions were summarized.

• Future development of microfluidic techniques for microparticle fabrication was discussed.

Abstract

Microfluidic techniques provide flexible strategies for fabrication of uniform advanced microparticles with well-tailored sizes, shapes, structures, and functions from controllable emulsion templates. This review highlights recent progress on controllable synthesis of microparticles using versatile microfluidic emulsions as templates. First, highly controllable and scalable microfluidic techniques for the generation of defined emulsions are introduced. Versatile microfluidic strategies for fabricating microparticles from diverse controllable emulsion templates are then summarized, including solid microparticles with spherical, non-spherical, and Janus configurations, porous microparticles with flexible pore structures, and compartmental microparticles with controlled internals. Finally, the future development of microfluidic techniques for microparticle fabrication is briefly discussed.

Graphical abstract

Keywords

Microfluidics; Microparticle; Microreactor; Emulsion; Template synthesis

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