Prediction of coating uniformity in batch fluidized-bed coating process--颗粒学报PARTICUOLOGY

Lipin, A. A., & Lipin, A. G. (2022). Prediction of coating uniformity in batch fluidized-bed coating process. Particuology, 61, 41-46. https://doi.org/10.1016/j.partic.2021.03.010

Prediction of coating uniformity in batch fluidized-bed coating process

Andrey A. Lipin ^*, Alexandr G. Lipin

Department of Processes and Apparatuses of Chemical Technology, Ivanovo State University of Chemistry and Technology, Ivanovo, Russia

10.1016/j.partic.2021.03.010

Volume 61, February 2022, Pages 41-46

Received 12 November 2020, Revised 17 March 2021, Accepted 18 March 2021, Available online 20 April 2021, Version of Record 27 October 2021.

E-mail: lipin.a@mail.ru

Highlights

• Prediction of coating uniformity.

• Numerical calculation of particle distribution according to degree of coverage.

• Modeling of batch fluidized-bed coating.

Abstract

Coating of particulate materials in fluidized beds is a widely used technique to eliminate particle agglomeration, provide slow release of an active substance, or protect active ingredients. When thin polymer shells are applied on a particle surface, it is important to determine the process parameters that provide coating uniformity. In this study, the degree of coverage, defined as the fraction of the coated surface of the particles, is proposed as a quantitative criterion of coating uniformity. A new model for the batch fluidized-bed coating process is presented. The model allows prediction of the function of particle distribution according to the degree of coverage at a given process time and thereby enables assessment of coating uniformity. An algorithm for the numerical solution of model equations for a batch fluidized-bed coater is described. The influences of the main process parameters on the coating uniformity were shown.

Graphical abstract

Keywords

Coating uniformity; Degree of coverage; Encapsulation; Fluidized-bed coating; Mathematical modeling

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