Pickering emulsions stabilized by biocompatible particles: A review of preparation, bioapplication, and perspective (Open Access)--颗粒学报PARTICUOLOGY

Zhang, T., Liu, F., Wu, J., & Ngai, T. (2022). Pickering emulsions stabilized by biocompatible particles: A review of preparation, bioapplication, and perspective. Particuology, 64, 110-120. https://doi.org/10.1016/j.partic.2021.07.003

Pickering emulsions stabilized by biocompatible particles: A review of preparation, bioapplication, and perspective (Open Access)

Tong Zhang ^a, Fuguo Liu ^{a b}, Jie Wu ^c, To Ngai ^a *

a Department of Chemistry, the Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China
b College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China
c State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China

10.1016/j.partic.2021.07.003

Volume 64, May 2022, Pages 110-120

Received 6 May 2021, Revised 25 June 2021, Accepted 22 July 2021, Available online 10 August 2021, Version of Record 17 December 2021.

E-mail: tongai@cuhk.edu.hk

Highlights

• Pickering emulsions based on biocompatible particles are summarized.

• Important examples of biocompatible Pickering emulsions are highlighted.

• Microcapsules and porous materials templated from Pickering emulsions are introduced.

• Applications in encapsulation, delivery, and tissue engineering are highlighted.

Abstract

The phenomenon of adsorption of solid particles at fluid interfaces to stabilize emulsions or foams have been known for more than a century. Today, particle-stabilized emulsions, often referred to as Pickering emulsions, are receiving growing attention as they are encountered in oil recovery and have long been used in personal care products and food industry. Over the past 10 years the focus of the Pickering emulsion has also increasingly shifted to biomedical applications with thanks to novel syntheses of a wide range of biocompatible particle stabilizers. Here, a brief overview of the development of biocompatible particles is given for Pickering emulsion stabilization, including alginate, poly(lactic-co-glycolic acid) (PLGA), and protein-based particles. The materials prepared by templating from emulsion stabilized with biocompatible particles include colloidal capsules and hierarchically porous materials. It is hoped that the understanding gained from the recent intense activity in the field will enable more researchers to modify existing materials and design new formulations, which would be beneficial for exploring more biological applications.

Graphical abstract

Keywords

Biocompatible particle; Pickering emulsion; High internal phase emulsion (HIPE); Porous structure

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