Copper-based nanomaterials as peroxidase candidates for intelligent colorimetric detection and antibacterial applications--颗粒学报PARTICUOLOGY

Huang, Y., Zhong, H., Jiang, C., Yang, J., Zhang, J., Zhao, F., & Liu, C. (2024). Copper-based nanomaterials as peroxidase candidates for intelligent colorimetric detection and antibacterial applications. Particuology, 84, 126-135. https://doi.org/10.1016/j.partic.2023.03.009

Copper-based nanomaterials as peroxidase candidates for intelligent colorimetric detection and antibacterial applications

Yanyan Huang ^a *, Huimin Zhong ^a, Cong Jiang ^a, Jiahui Yang ^a, Jingwen Zhang ^a, Fei Zhao ^a, Chaoqun Liu ^b *

a College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, 210037, China
b College of Pharmacy, Institutes of Environment and Medicine, Henan University, Kaifeng, 475004, China

10.1016/j.partic.2023.03.009

Volume 84, January 2024, Pages 126-135

Received 10 January 2023, Revised 25 February 2023, Accepted 9 March 2023, Available online 29 March 2023, Version of Record 11 April 2023.

E-mail: huangyanyan0819@njfu.edu.cn; cqliu@henu.edu.cn

Highlights

• Cu–O–C structure of CuTA was similar to the Fe–N–C structure of natural heme enzymes.

• CuTA nanomaterial possessed excellent peroxidase-like catalytic activity and stability.

• CuTA nanozyme could detect H₂O₂ with a smartphone and catalyze the degradation of RhB.

• Structure and catalytic properties make CuTA effectively inhibit bacterial growth under a low H₂O₂ level.

Abstract

With natural polyphenol compound tannic acid (TA) as the ingredient, copper tannate (CuTA) nanolayer material was formed by self-assembly under the conditions of heating and copper ion. Copper ion and tannic acid could coordinate to form Cu–O–C structure which was similar to the Fe–N–C structure of natural heme enzymes. In addition, the obtained CuTA nanomaterial possessed excellent peroxidase-like catalytic activity and stability. Based on this excellent enzymatic activity, CuTA nanomaterials could be used for colorimetric detection of hydrogen peroxide with a smartphone and decomposition of organic dyes. Based on the structural characteristics and catalytic activity, the copper tannate nanozymes could also serve as potential antibacterial reagents to effectively inhibit the growth of gram-negative and positive bacteria in a low hydrogen peroxide level. This work may promote the exploration of novel peroxidase mimetics and broaden the applications of nanozymes.

Graphical abstract

Keywords

Nanozyme; Colorimetric detection; Smartphone; Antibacteria

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