- Volumes 84-95 (2024)
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Volumes 72-83 (2023)
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Volume 83
Pages 1-258 (December 2023)
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Volume 82
Pages 1-204 (November 2023)
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Volume 81
Pages 1-188 (October 2023)
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Volume 80
Pages 1-202 (September 2023)
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Volume 79
Pages 1-172 (August 2023)
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Volume 78
Pages 1-146 (July 2023)
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Volume 77
Pages 1-152 (June 2023)
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Volume 76
Pages 1-176 (May 2023)
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Volume 75
Pages 1-228 (April 2023)
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Volume 74
Pages 1-200 (March 2023)
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Volume 73
Pages 1-138 (February 2023)
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Volume 72
Pages 1-144 (January 2023)
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Volume 83
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Volumes 60-71 (2022)
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Volume 71
Pages 1-108 (December 2022)
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Volume 70
Pages 1-106 (November 2022)
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Volume 69
Pages 1-122 (October 2022)
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Volume 68
Pages 1-124 (September 2022)
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Volume 67
Pages 1-102 (August 2022)
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Volume 66
Pages 1-112 (July 2022)
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Volume 65
Pages 1-138 (June 2022)
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Volume 64
Pages 1-186 (May 2022)
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Volume 63
Pages 1-124 (April 2022)
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Volume 62
Pages 1-104 (March 2022)
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Volume 61
Pages 1-120 (February 2022)
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Volume 60
Pages 1-124 (January 2022)
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Volume 71
- Volumes 54-59 (2021)
- Volumes 48-53 (2020)
- Volumes 42-47 (2019)
- Volumes 36-41 (2018)
- Volumes 30-35 (2017)
- Volumes 24-29 (2016)
- Volumes 18-23 (2015)
- Volumes 12-17 (2014)
- Volume 11 (2013)
- Volume 10 (2012)
- Volume 9 (2011)
- Volume 8 (2010)
- Volume 7 (2009)
- Volume 6 (2008)
- Volume 5 (2007)
- Volume 4 (2006)
- Volume 3 (2005)
- Volume 2 (2004)
- Volume 1 (2003)
• Sodium alginate-based microcapsules prepared by economical sonochemical method.
• Microcapsules have high encapsulation rate and good biocompatibility.
• Excess Curcumin (CUR) and ethyl acetate can be recycled and reused.
• CUR-loaded microcapsules (FA-RSMCs@CUR) exhibit good antibacterial properties.
• FA-RSMCs@CUR exhibit targeted and pH/reduction dual-triggered release properties.
In this study, sodium alginate (SA), a non-toxic natural polysaccharide with good biocompatibility and biodegradability, was developed for targeted delivery of curcumin (CUR) in tumor therapy. The strategy is to sulfhydrylate the folic acid (FA) modified SA, and the CUR dissolved in ethyl acetate (EAC) phase is coated in microcapsules by a quick, efficient and environment-friendly sonochemical method. The EAC in the microcapsule core is volatile, which can be recycled and reused to reduce cost. The prepared microcapsules (FA-RSMCs@CUR) exhibited similar toxicity to free curcumin in anti-tumour evaluation in vitro. FA-RSMCs@CUR also exhibited effective antibacterial properties in the antibacterial evaluation in vitro. It is expected to become a low-cost tumor targeting vector in the future, and has the potential to be promoted in clinical application.