Collagen-reinforced polystyrene/polycaprolactone membranes with nickel oxide nanoparticles: Enhanced mechanical, thermal, and antibacterial properties for antibacterial applications--颗粒学报PARTICUOLOGY

Ren, T., Ye, Z., Li, H., Cui, Q., Zhang, H., Banihashemian, S. M., & Guo, Z. (2025). Collagen-reinforced polystyrene/polycaprolactone membranes with nickel oxide nanoparticles: Enhanced mechanical, thermal, and antibacterial properties for antibacterial applications. Particuology, 96, 193-202. https://doi.org/10.1016/j.partic.2024.11.006

Collagen-reinforced polystyrene/polycaprolactone membranes with nickel oxide nanoparticles: Enhanced mechanical, thermal, and antibacterial properties for antibacterial applications

Tingting Ren^{a e *}, Zhangjing Ye^b, Haoran Li^{a e}, Qiqi Cui^{a e}, Hongxia Zhang^{c d *}, Seyedeh Maryam Banihashemian^f, Zhijun Guo^{a e *}

a College of Food Science and Engineering, Yanbian University, Yanbian, 133002, China
b College of Food Science and Engineering, Dalian Ocean University, Dalian, 116023, China
c Department of Food Nanotechnology, Research Institute of Food Science and Technology (RIFST), PO Box: 91895-157-356, Mashhad, Iran
d Particle and Interfacial Technology Group (PaInT), Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Gent, 9000, Belgium
e Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, 133002, China
f MEMS&NEMS Laboratory, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran

10.1016/j.partic.2024.11.006

Volume 96, January 2025, Pages 193-202

Received 8 October 2024, Revised 8 November 2024, Accepted 11 November 2024, Available online 28 November 2024, Version of Record 10 December 2024.

E-mail: rtt2642968412@gmail.com; zhanghongxia326@hotmail.com; guozhijunvip@163.com; zjguo@ybu.edu.cn

Highlights

• Squid collagen boosts membrane strength by 86% in electrospinning.

• NiO nanoparticles improved antibacterial activity against E. coli and S. aureus.

• Collagen and NiO improve thermal stability, verified by DSC and TGA.

• The membrane offered controlled release capabilities, suitable for drug delivery.

Abstract

Electrospinning technology was employed to fabricate a novel composite membrane integrating collagen from Peruvian squid skin with polystyrene (PS), polycaprolactone (PCL), and green-synthesized nickel oxide (NiO) nanoparticles (PS/PCL/CO/NiO). The addition of collagen (CO) and NiO nanoparticles significantly enhanced the membrane's hydrophobicity, as evidenced by an increase in the water contact angle from 124.8 ± 0.6° to 131.2 ± 1.2°. Mechanical properties showed substantial improvement, with tensile strength increasing by 86% (from 5.05 ± 1.6 MPa to 9.39 ± 1.4 MPa) and elongation at break improving by 48% compared to conventional NiO membranes. Thermal analysis indicated increased stability, with a higher endothermic peak and an enthalpy increase from 6.885 J/g to 8.584 J/g. Antibacterial assays revealed strong efficacy against Escherichia coli and Staphylococcus aureus, reducing bacterial growth by over 90%. The enhanced hydrophobicity, mechanical strength, thermal stability, and antibacterial activity of PS/PCL/CO/NiO membranes make them highly promising for applications in tissue engineering, wound dressings, and water treatment.

Graphical abstract

Keywords

Electrospun fibers membranes; Squid skin; Collagen; NiO nanoparticle; Escherichia coli; Staphylococcus aureus

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