Solid-liquid two-phase flow pipeline transportation is widely utilized in mine backfilling and concrete pumping. Conventional numerical simulations commonly overlook inter-particle adhesion in high-viscosity materials, failing to precisely capture the dynamic evolution of particle contact-adhesion. To tackle this technical issue, the Johnson-Kendall-Roberts (JKR) adhesive contact theory is integrated into the coupled Lattice Boltzmann Method-Immersed Boundary Method-Discrete Element Method (LBM-IBM-DEM) framework, and the influences of surface energy, particle size random coefficient, inlet velocity and particle number on fluid-solid coupling and agglomeration behaviors are systematically explored. Results indicate that adhesive particles maintain high collision frequency in bend pipes and reduce the global flow velocity; medium and high adhesion present similar collision frequency while high adhesion generates stronger agglomeration and flow field hindrance; a wider size distribution intensifies particle collisions and agglomeration; particle agglomeration is governed by both collision frequency and flow velocity with distinct aggregation patterns; a large particle number fills the bend pipe cross-section and drastically elevates the blockage risk. This work unravels the adhesion-dominated macroscopic blockage mechanism, laying a theoretical foundation for anti-blockage design in pipeline transportation engineering.